Board Thread:Questions and Answers/@comment-26525901-20161218232837/@comment-27701762-20161219163545

Sure. What you do in the Neutral Route doesn't actually affect what you can do when you Reset, with the exception that completing a Neutral run in general allows you to reach the True Pacifist ending. There will only be two changes. First, a lot of dialogue will change. Second, if you try to complete a Neutral run again, you will not fight Photoshop Flowey again.